Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

Proliferative reactive gliosis is compatible with glial metabolic support and neuronal function

<p>Abstract</p> <p>Background</p> <p>The response of mammalian glial cells to chronic degeneration and trauma is hypothesized to be incompatible with support of neuronal function in the central nervous system (CNS) and retina. To test this hypothesis, we developed an in...

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Bibliographic Details
Main Authors: Fero Matthew, Chien Wei-Ming, Baehr Wolfgang, Jiang Li, Ferrell W Drew, Swan Alex, Vázquez-Chona Félix R, Marc Robert E, Levine Edward M
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Neuroscience
Subjects:
reactive gliosis
retinal degeneration
neuronal degeneration
GFAP
Müller glia
p27Kip1
CDKN1B
intermediate filaments
Online Access:http://www.biomedcentral.com/1471-2202/12/98

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http://www.biomedcentral.com/1471-2202/12/98

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