Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strength...

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Bibliographic Details
Main Authors: Rémy Durand, Virginie Prendki, Johann Cailhol, Véronique Hubert, Pascal Ralaimazava, Laurent Massias, Olivier Bouchaud, Jacques Le Bras
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2008-02-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/14/2/07-0945_article
Description
Summary:We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.
ISSN:1080-6040
1080-6059