Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure

We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strength...

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Main Authors: Rémy Durand, Virginie Prendki, Johann Cailhol, Véronique Hubert, Pascal Ralaimazava, Laurent Massias, Olivier Bouchaud, Jacques Le Bras
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2008-02-01
Series:Emerging Infectious Diseases
Subjects:
Plasmodium falciparum
atovaquone-proguanil
therapeutic failure
dispatch
France
Democratic Republic of Congo
Online Access:https://wwwnc.cdc.gov/eid/article/14/2/07-0945_article
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spelling doaj-047f7d3f6732415fa46fc359504aaf502020-11-24T22:07:36ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-02-0114232032210.3201/eid1402.070945Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment FailureRémy DurandVirginie PrendkiJohann CailholVéronique HubertPascal RalaimazavaLaurent MassiasOlivier BouchaudJacques Le BrasWe noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.https://wwwnc.cdc.gov/eid/article/14/2/07-0945_articlePlasmodium falciparumatovaquone-proguaniltherapeutic failuredispatchFranceDemocratic Republic of Congo
collection DOAJ
language English
format Article
sources DOAJ
author Rémy Durand
Virginie Prendki
Johann Cailhol
Véronique Hubert
Pascal Ralaimazava
Laurent Massias
Olivier Bouchaud
Jacques Le Bras
spellingShingle Rémy Durand
Virginie Prendki
Johann Cailhol
Véronique Hubert
Pascal Ralaimazava
Laurent Massias
Olivier Bouchaud
Jacques Le Bras
Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
Emerging Infectious Diseases
Plasmodium falciparum
atovaquone-proguanil
therapeutic failure
dispatch
France
Democratic Republic of Congo
author_facet Rémy Durand
Virginie Prendki
Johann Cailhol
Véronique Hubert
Pascal Ralaimazava
Laurent Massias
Olivier Bouchaud
Jacques Le Bras
author_sort Rémy Durand
title Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_short Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_full Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_fullStr Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_full_unstemmed Plasmodium falciparum Malaria and Atovaquone-Proguanil Treatment Failure
title_sort plasmodium falciparum malaria and atovaquone-proguanil treatment failure
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2008-02-01
description We noticed overrepresentation of atovaquone-proguanil therapeutic failures among Plasmodium falciparum–infected travelers weighing >100 kg. We report here 1 of these cases, which was not due to resistant parasites or impaired drug bioavailability. The follow-up of such patients should be strengthened.
topic Plasmodium falciparum
atovaquone-proguanil
therapeutic failure
dispatch
France
Democratic Republic of Congo
url https://wwwnc.cdc.gov/eid/article/14/2/07-0945_article
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AT virginieprendki plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT johanncailhol plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT veroniquehubert plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT pascalralaimazava plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT laurentmassias plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT olivierbouchaud plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
AT jacqueslebras plasmodiumfalciparummalariaandatovaquoneproguaniltreatmentfailure
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