A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation

A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation

We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic s...

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Main Authors: Dan Han, Yuqian Sun, Rong Xie, Xiaojian Zhu, Zhaodong Zhong
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2021/8878803
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spelling doaj-04870af87dd94ca2bbe963b2d351aa552021-03-29T00:08:46ZengHindawi LimitedCase Reports in Hematology2090-65792021-01-01202110.1155/2021/8878803A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical TransplantationDan Han0Yuqian Sun1Rong Xie2Xiaojian Zhu3Zhaodong Zhong4Department of HematologyPeking University Institute of HematologyDepartment of HematologyDepartment of HematologyDepartment of HematologyWe report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic shock and multiple organ failure. It was concluded that the disease condition of this COVID-19 patient after transplantation was serious, complex, and variable, with poor prognosis.http://dx.doi.org/10.1155/2021/8878803
collection DOAJ
language English
format Article
sources DOAJ
author Dan Han
Yuqian Sun
Rong Xie
Xiaojian Zhu
Zhaodong Zhong
spellingShingle Dan Han
Yuqian Sun
Rong Xie
Xiaojian Zhu
Zhaodong Zhong
A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
Case Reports in Hematology
author_facet Dan Han
Yuqian Sun
Rong Xie
Xiaojian Zhu
Zhaodong Zhong
author_sort Dan Han
title A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_short A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_full A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_fullStr A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_full_unstemmed A Case of Severe COVID-19 in a Patient with Acute Graft-versus-Host Disease after Haploidentical Transplantation
title_sort case of severe covid-19 in a patient with acute graft-versus-host disease after haploidentical transplantation
publisher Hindawi Limited
series Case Reports in Hematology
issn 2090-6579
publishDate 2021-01-01
description We report a case of coronavirus disease 2019 (COVID-19) after haploidentical transplantation with acute graft-versus-host disease (aGVHD). COVID-19 and aGVHD were improved under treatment with arbidol, remdesivir, methylprednisolone, and ruxolitinib. However, eventually, the patient died of septic shock and multiple organ failure. It was concluded that the disease condition of this COVID-19 patient after transplantation was serious, complex, and variable, with poor prognosis.
url http://dx.doi.org/10.1155/2021/8878803
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