ProNGF and Neurodegeneration in Alzheimer’s Disease
Profound and early basal forebrain cholinergic neuron (BFCN) degeneration is a hallmark of Alzheimer’s disease (AD). Loss of synapses between basal forebrain and hippocampal and cortical target tissue correlates highly with the degree of dementia and is thought to be a major contributor to memory lo...
Main Authors: | Margaret Fahnestock, Arman Shekari |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-02-01
|
Series: | Frontiers in Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnins.2019.00129/full |
Similar Items
-
ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels
by: Maria S. Ioannou, et al.
Published: (2017-03-01) -
Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease
by: Erika Kropf, et al.
Published: (2021-08-01) -
NOS induction by NGF in basal forebrain cholinergic neurones: evidence for regulation of brain NOS by a neurotrophin
by: David M. Holtzman, et al.
Published: (1994-11-01) -
Expression of NGF/proNGF and Their Receptors TrkA, p75NTR and Sortilin in Melanoma
by: Dowdell, A., et al.
Published: (2022) -
Expression of NGF/proNGF and Their Receptors TrkA, p75NTR and Sortilin in Melanoma
by: Dowdell, A., et al.
Published: (2022)