Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays marked in vitro neurotoxicity. No components have...

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Bibliographic Details
Main Authors: Carmel M. Barber, Muhamad Rusdi Ahmad Rusmili, Wayne C. Hodgson
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Toxins
Subjects:
α-Elapitoxin-Ot1a
Oxyuranus temporalis
postsynaptic neurotoxin
antivenom
snake
Online Access:http://www.mdpi.com/2072-6651/8/3/58

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