Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients

Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients

There is strong interest in the nature of the neutralizing antibody response against SARS-CoV-2 in infected individuals. For vaccine development, it is especially important which antibodies confer protection against SARS-CoV-2, if there is a phenomenon called antibody-dependent enhancemen...

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Main Authors: Natalia Ruetalo, Ramona Businger, Karina Althaus, Simon Fink, Felix Ruoff, Michaela Pogoda, Angelika Iftner, Tina Ganzenmüller, Klaus Hamprecht, Bertram Flehmig, Tamam Bakchoul, Markus F. Templin, Michael Schindler
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mSphere
Online Access:https://journals.asm.org/doi/10.1128/mSphere.01145-20
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spelling doaj-04a7c3e4823c4a918fd867a934553a0b2021-09-21T20:22:52ZengAmerican Society for MicrobiologymSphere2379-50422021-02-016110.1128/mSphere.01145-20Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 PatientsNatalia Ruetalo0Ramona Businger1Karina Althaus2Simon Fink3Felix Ruoff4Michaela Pogoda5Angelika Iftner6Tina Ganzenmüller7Klaus Hamprecht8Bertram Flehmig9Tamam Bakchoul10Markus F. Templin11Michael Schindler12https://orcid.org/0000-0001-8989-5813Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, GermanyInstitute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, GermanyInstitute for Transfusion Medicine, University Hospital Tübingen, Tübingen, GermanyNMI, Reutlingen, GermanyNMI, Reutlingen, GermanyInstitute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, GermanyInstitute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, GermanyInstitute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, GermanyInstitute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, GermanyMediagnost GmbH, Reutlingen, GermanyInstitute for Transfusion Medicine, University Hospital Tübingen, Tübingen, GermanyNMI, Reutlingen, GermanyInstitute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, Germany There is strong interest in the nature of the neutralizing antibody response against SARS-CoV-2 in infected individuals. For vaccine development, it is especially important which antibodies confer protection against SARS-CoV-2, if there is a phenomenon called antibody-dependent enhancement (ADE) of infection, and if there is cross-protection by antibodies directed against seasonal coronaviruses.https://journals.asm.org/doi/10.1128/mSphere.01145-20
collection DOAJ
language English
format Article
sources DOAJ
author Natalia Ruetalo
Ramona Businger
Karina Althaus
Simon Fink
Felix Ruoff
Michaela Pogoda
Angelika Iftner
Tina Ganzenmüller
Klaus Hamprecht
Bertram Flehmig
Tamam Bakchoul
Markus F. Templin
Michael Schindler
spellingShingle Natalia Ruetalo
Ramona Businger
Karina Althaus
Simon Fink
Felix Ruoff
Michaela Pogoda
Angelika Iftner
Tina Ganzenmüller
Klaus Hamprecht
Bertram Flehmig
Tamam Bakchoul
Markus F. Templin
Michael Schindler
Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
mSphere
author_facet Natalia Ruetalo
Ramona Businger
Karina Althaus
Simon Fink
Felix Ruoff
Michaela Pogoda
Angelika Iftner
Tina Ganzenmüller
Klaus Hamprecht
Bertram Flehmig
Tamam Bakchoul
Markus F. Templin
Michael Schindler
author_sort Natalia Ruetalo
title Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
title_short Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
title_full Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
title_fullStr Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
title_full_unstemmed Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients
title_sort antibody response against sars-cov-2 and seasonal coronaviruses in nonhospitalized covid-19 patients
publisher American Society for Microbiology
series mSphere
issn 2379-5042
publishDate 2021-02-01
description There is strong interest in the nature of the neutralizing antibody response against SARS-CoV-2 in infected individuals. For vaccine development, it is especially important which antibodies confer protection against SARS-CoV-2, if there is a phenomenon called antibody-dependent enhancement (ADE) of infection, and if there is cross-protection by antibodies directed against seasonal coronaviruses.
url https://journals.asm.org/doi/10.1128/mSphere.01145-20
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