Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics

Summary: Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions (for instance, with immune checkpoint inhibitors) can provide significant benefits for patients. However, our knowledge of which interactions occur i...

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Bibliographic Details
Main Authors:	Manu P. Kumar, Jinyan Du, Georgia Lagoudas, Yang Jiao, Andrew Sawyer, Daryl C. Drummond, Douglas A. Lauffenburger, Andreas Raue
Format:	Article
Language:	English
Published:	Elsevier 2018-11-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S221112471831636X

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