Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion

Human predecidual stromal cells are mesenchymal stromal/stem cells and have a therapeutic effect in an immune-based mouse model of recurrent spontaneous abortion

Abstract Background Human decidual stromal cells (DSCs) are involved in the maintenance and development of pregnancy, in which they play a key role in the induction of immunological maternal–fetal tolerance. Precursors of DSCs (preDSCs) are located around the vessels, and based on their antigen phen...

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Bibliographic Details
Main Authors: Raquel Muñoz-Fernández, Claudia De La Mata, Francisco Requena, Francisco Martín, Pablo Fernandez-Rubio, Tatiana Llorca, Maria José Ruiz-Magaña, Carmen Ruiz-Ruiz, Enrique G. Olivares
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Stem Cell Research & Therapy
Subjects:
Clone cells
Decidua
Immune tolerance
Immunotherapy
Mesenchymal stromal cells
Predecidual stromal cells
Online Access:http://link.springer.com/article/10.1186/s13287-019-1284-z

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