Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis
Abstract Felidae as definitive hosts for Toxoplasma gondii play a major role in transmission to all warm-blooded animals trough oocysts dissemination. Therefore the current comprehensive study was performed to determine the global status of T. gondii infection in domestic and wild felids aiming to p...
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doaj-04ed203d5fb84845aa6e69039e8f38502021-05-09T11:35:05ZengNature Publishing GroupScientific Reports2045-23222021-05-0111111110.1038/s41598-021-89031-8Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysisKareem Hatam-Nahavandi0Rafael Calero-Bernal1Mohammad Taghi Rahimi2Abdol Sattar Pagheh3Mehdi Zarean4Asiyeh Dezhkam5Ehsan Ahmadpour6School of Medicine, Iranshahr University of Medical SciencesSALUVET, Animal Health Department, Faculty of Veterinary Sciences, Complutense University of MadridCenter for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical SciencesInfectious Diseases Research Canter, Birjand University of Medical SciencesDepartment of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical SciencesSchool of Medicine, Iranshahr University of Medical SciencesInfectious and Tropical Diseases Research Center, Tabriz University of Medical SciencesAbstract Felidae as definitive hosts for Toxoplasma gondii play a major role in transmission to all warm-blooded animals trough oocysts dissemination. Therefore the current comprehensive study was performed to determine the global status of T. gondii infection in domestic and wild felids aiming to provide comprehensive data of interest for further intervention approaching the One Health perspective. Different databases were searched by utilizing particular key words for publications related to T. gondii infecting domestic and wild feline host species, worldwide, from 1970 to 2020. The review of 337 reports showed that the seroprevalence of T. gondii in domestic cats and wild felids was estimated in 37.5% (95% CI 34.7–40.3) (I 2 = 98.3%, P < 0.001) and 64% (95% CI 60–67.9) (I 2 = 88%, P < 0.0001), respectively. The global pooled prevalence of oocysts in the fecal examined specimens from domestic cats was estimated in 2.6% (95% CI 1.9–3.3) (I 2 = 96.1%, P < 0.0001), and that in fecal samples from wild felids was estimated in 2.4% (95% CI 1.1–4.2) (I 2 = 86.4%, P < 0.0001). In addition, from 13,252 examined soil samples in 14 reviewed studies, the pooled occurrence of T. gondii oocysts was determined in 16.2% (95% CI 7.66–27.03%). The observed high rates of anti-T. gondii antibodies seroprevalence levels and oocyst excretion frequency in the felids, along with soil (environmental) contamination with oocysts may constitute a potential threat to animal and public health, and data will result of interest in further prophylaxis programs.https://doi.org/10.1038/s41598-021-89031-8 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Kareem Hatam-Nahavandi Rafael Calero-Bernal Mohammad Taghi Rahimi Abdol Sattar Pagheh Mehdi Zarean Asiyeh Dezhkam Ehsan Ahmadpour |
spellingShingle |
Kareem Hatam-Nahavandi Rafael Calero-Bernal Mohammad Taghi Rahimi Abdol Sattar Pagheh Mehdi Zarean Asiyeh Dezhkam Ehsan Ahmadpour Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis Scientific Reports |
author_facet |
Kareem Hatam-Nahavandi Rafael Calero-Bernal Mohammad Taghi Rahimi Abdol Sattar Pagheh Mehdi Zarean Asiyeh Dezhkam Ehsan Ahmadpour |
author_sort |
Kareem Hatam-Nahavandi |
title |
Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
title_short |
Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
title_full |
Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
title_fullStr |
Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
title_full_unstemmed |
Toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
title_sort |
toxoplasma gondii infection in domestic and wild felids as public health concerns: a systematic review and meta-analysis |
publisher |
Nature Publishing Group |
series |
Scientific Reports |
issn |
2045-2322 |
publishDate |
2021-05-01 |
description |
Abstract Felidae as definitive hosts for Toxoplasma gondii play a major role in transmission to all warm-blooded animals trough oocysts dissemination. Therefore the current comprehensive study was performed to determine the global status of T. gondii infection in domestic and wild felids aiming to provide comprehensive data of interest for further intervention approaching the One Health perspective. Different databases were searched by utilizing particular key words for publications related to T. gondii infecting domestic and wild feline host species, worldwide, from 1970 to 2020. The review of 337 reports showed that the seroprevalence of T. gondii in domestic cats and wild felids was estimated in 37.5% (95% CI 34.7–40.3) (I 2 = 98.3%, P < 0.001) and 64% (95% CI 60–67.9) (I 2 = 88%, P < 0.0001), respectively. The global pooled prevalence of oocysts in the fecal examined specimens from domestic cats was estimated in 2.6% (95% CI 1.9–3.3) (I 2 = 96.1%, P < 0.0001), and that in fecal samples from wild felids was estimated in 2.4% (95% CI 1.1–4.2) (I 2 = 86.4%, P < 0.0001). In addition, from 13,252 examined soil samples in 14 reviewed studies, the pooled occurrence of T. gondii oocysts was determined in 16.2% (95% CI 7.66–27.03%). The observed high rates of anti-T. gondii antibodies seroprevalence levels and oocyst excretion frequency in the felids, along with soil (environmental) contamination with oocysts may constitute a potential threat to animal and public health, and data will result of interest in further prophylaxis programs. |
url |
https://doi.org/10.1038/s41598-021-89031-8 |
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