Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation.

Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation.

BACKGROUND/AIMS:Bleeding tendency, coagulopathy and platelet disorders are recurrent manifestations in snakebites occurring worldwide. We reasoned that by damaging tissues and/or activating cells at the site of the bite and systemically, snake venom toxins might release or decrypt tissue factor (TF)...

Full description

Bibliographic Details
Main Authors: Karine M Yamashita, André F Alves, Katia C Barbaro, Marcelo L Santoro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4022520?pdf=render

Similar Items

Similar Items