Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes

We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune...

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Main Authors:	Gabriel I. Parra, Kim Y. Green
Format:	Article
Language:	English
Published:	Centers for Disease Control and Prevention 2014-06-01
Series:	Emerging Infectious Diseases
Subjects:	Norovirus diarrhea immunity genotype viruses
Online Access:	https://wwwnc.cdc.gov/eid/article/20/6/13-1627_article

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spelling	doaj-050fad6b4fe64e11b7344ccd5fd314652020-11-25T02:34:01ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592014-06-012061016101810.3201/eid2006.131627Sequential Gastroenteritis Episodes Caused by 2 Norovirus GenotypesGabriel I. ParraKim Y. GreenWe investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.https://wwwnc.cdc.gov/eid/article/20/6/13-1627_articleNorovirusdiarrheaimmunitygenotypeviruses
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Gabriel I. Parra Kim Y. Green
spellingShingle	Gabriel I. Parra Kim Y. Green Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes Emerging Infectious Diseases Norovirus diarrhea immunity genotype viruses
author_facet	Gabriel I. Parra Kim Y. Green
author_sort	Gabriel I. Parra
title	Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_short	Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full	Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_fullStr	Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_full_unstemmed	Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes
title_sort	sequential gastroenteritis episodes caused by 2 norovirus genotypes
publisher	Centers for Disease Control and Prevention
series	Emerging Infectious Diseases
issn	1080-6040 1080-6059
publishDate	2014-06-01
description	We investigated sequential episodes of acute norovirus gastroenteritis in a young child within an 11-month period. The infections were caused by 2 distinct genotypes (GII.4 and GII.6). Failure to achieve cross-protective immunity was linked to absence of an enduring and cross-reactive mucosal immune response, a critical consideration for vaccine design.
topic	Norovirus diarrhea immunity genotype viruses
url	https://wwwnc.cdc.gov/eid/article/20/6/13-1627_article
work_keys_str_mv	AT gabrieliparra sequentialgastroenteritisepisodescausedby2norovirusgenotypes AT kimygreen sequentialgastroenteritisepisodescausedby2norovirusgenotypes
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Sequential Gastroenteritis Episodes Caused by 2 Norovirus Genotypes

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