Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling.

Hox paralog group 2 genes control the migration of mouse pontine neurons through slit-robo signaling.

The pontine neurons (PN) represent a major source of mossy fiber projections to the cerebellum. During mouse hindbrain development, PN migrate tangentially and sequentially along both the anteroposterior (AP) and dorsoventral (DV) axes. Unlike DV migration, which is controlled by the Netrin-1/Dcc at...

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Bibliographic Details
Main Authors: Marc J Geisen, Thomas Di Meglio, Massimo Pasqualetti, Sebastien Ducret, Jean-François Brunet, Alain Chedotal, Filippo M Rijli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2422855?pdf=render

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http://europepmc.org/articles/PMC2422855?pdf=render

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