Clearing the corpses: regulatory mechanisms, novel tools, and therapeutic potential of harnessing microglial phagocytosis in the diseased brain

Clearing the corpses: regulatory mechanisms, novel tools, and therapeutic potential of harnessing microglial phagocytosis in the diseased brain

Apoptosis is a widespread phenomenon that occurs in the brain in both physiological and pathological conditions. Dead cells must be quickly removed to avoid the further toxic effects they exert in the parenchyma, a process executed by microglia, the brain professional phagocytes. Although phagocytos...

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Bibliographic Details
Main Authors: Irune Diaz-Aparicio, Sol Beccari, Oihane Abiega, Amanda Sierra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
microglia; phagocytosis; apoptosis; impairment; epilepsy; brain diseases; neurodegeneration; inflammation; neuroinflammation
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=10;spage=1533;epage=1539;aulast=Diaz-Aparicio

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=10;spage=1533;epage=1539;aulast=Diaz-Aparicio

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