Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

Summary: Dysregulated immune cell responses have been linked to the severity of coronavirus disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were currently unknown. Herein, we reveal that the Immunoglobulin-like fold ectodomain o...

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Bibliographic Details
Main Authors: Ziliang Zhou, Chunliu Huang, Zhechong Zhou, Zhaoxia Huang, Lili Su, Sisi Kang, Xiaoxue Chen, Qiuyue Chen, Suhua He, Xia Rong, Fei Xiao, Jun Chen, Shoudeng Chen
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Immunology
Virology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001553

Internet

http://www.sciencedirect.com/science/article/pii/S2589004221001553

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