Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes
Summary: Dysregulated immune cell responses have been linked to the severity of coronavirus disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were currently unknown. Herein, we reveal that the Immunoglobulin-like fold ectodomain o...
Main Authors: | Ziliang Zhou, Chunliu Huang, Zhechong Zhou, Zhaoxia Huang, Lili Su, Sisi Kang, Xiaoxue Chen, Qiuyue Chen, Suhua He, Xia Rong, Fei Xiao, Jun Chen, Shoudeng Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221001553 |
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