Variability of CSF Alzheimer's disease biomarkers: implications for clinical practice.

BACKGROUND:Cerebrospinal fluid (CSF) biomarkers are increasingly being used for diagnosis of Alzheimer's disease (AD). OBJECTIVE:We investigated the influence of CSF intralaboratory and interlaboratory variability on diagnostic CSF-based AD classification of subjects and identified causes of th...

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Bibliographic Details
Main Authors: Stephanie J B Vos, Pieter Jelle Visser, Frans Verhey, Pauline Aalten, Dirk Knol, Inez Ramakers, Philip Scheltens, Marcel G M Olde Rikkert, Marcel M Verbeek, Charlotte E Teunissen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4069102?pdf=render