Removal of Protein-Bound Uremic Toxins Using Binding Competitors in Hemodialysis: A Narrative Review

Removal of Protein-Bound Uremic Toxins Using Binding Competitors in Hemodialysis: A Narrative Review

Removal of protein-bound uremic toxins (PBUTs) during conventional dialysis is insufficient. PBUTs are associated with comorbidities and mortality in dialysis patients. Albumin is the primary carrier for PBUTs and only a small free fraction of PBUTs are dialyzable. In the past, we proposed a novel m...

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Bibliographic Details
Main Authors: Vaibhav Maheshwari, Xia Tao, Stephan Thijssen, Peter Kotanko
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxins
Subjects:
binding competition
hemodialysis
intoxication
indoxyl sulfate
p-cresyl sulfate
CMPF
Online Access:https://www.mdpi.com/2072-6651/13/9/622

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