Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells

Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.

Bibliographic Details
Main Authors:	Aki Stubb, Camilo Guzmán, Elisa Närvä, Jesse Aaron, Teng-Leong Chew, Markku Saari, Mitro Miihkinen, Guillaume Jacquemet, Johanna Ivaska
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-12611-w

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spelling	doaj-054ff7d405564aaf959a9efd06915fc42021-05-11T12:16:58ZengNature Publishing GroupNature Communications2041-17232019-10-0110111510.1038/s41467-019-12611-wSuperresolution architecture of cornerstone focal adhesions in human pluripotent stem cellsAki Stubb0Camilo Guzmán1Elisa Närvä2Jesse Aaron3Teng-Leong Chew4Markku Saari5Mitro Miihkinen6Guillaume Jacquemet7Johanna Ivaska8Turku Bioscience Centre, University of Turku and Åbo Akademi UniversityTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityAdvanced Imaging Center, HHMI Janelia Research CampusAdvanced Imaging Center, HHMI Janelia Research CampusTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityTurku Bioscience Centre, University of Turku and Åbo Akademi UniversityPluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.https://doi.org/10.1038/s41467-019-12611-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska
spellingShingle	Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells Nature Communications
author_facet	Aki Stubb Camilo Guzmán Elisa Närvä Jesse Aaron Teng-Leong Chew Markku Saari Mitro Miihkinen Guillaume Jacquemet Johanna Ivaska
author_sort	Aki Stubb
title	Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_short	Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_full	Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_fullStr	Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_full_unstemmed	Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
title_sort	superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-10-01
description	Pluripotent stem cell colonies are encircled by large cornerstone focal adhesions (FAs). Here, using super-resolution imaging, the authors describe features in the nanoscale makeup of these stable FAs such as inverted vinculin, lateral talin segregation and distinct kank protein distributions.
url	https://doi.org/10.1038/s41467-019-12611-w
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Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells

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