Potential impact of epidural labor analgesia on the outcomes of neonates and children
Abstract. This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including “ELA,” “ELA and neonatal outcomes,” “ELA and children's development,” and “ELA and children's...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2020-10-01
|
Series: | Chinese Medical Journal |
Online Access: | http://journals.lww.com/10.1097/CM9.0000000000000900 |
id |
doaj-05872d4dab3b4afb9c9c1e5b6dd428b8 |
---|---|
record_format |
Article |
spelling |
doaj-05872d4dab3b4afb9c9c1e5b6dd428b82020-12-02T08:02:06ZengWolters KluwerChinese Medical Journal0366-69992542-56412020-10-01133192353235810.1097/CM9.0000000000000900202010050-00016Potential impact of epidural labor analgesia on the outcomes of neonates and childrenZhi-Hua Liu0Dong-Xin Wang1Li-Shao Guo2Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.Abstract. This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including “ELA,” “ELA and neonatal outcomes,” “ELA and children's development,” and “ELA and children's neurocognitive development” were used to search articles published in PubMed database up to October 2019. Original articles and reviews regarding potential influences of ELA on neonates and children were identified. Relevant references of the selected articles were also screened. The anesthetics used during ELA can be absorbed, enter the fetus, and produce neonatal depression; however, these effects are less severe than those during systematic opioid analgesia. The impact of anesthetic exposure during ELA on children's neurodevelopment has not been fully studied, but would be mild if any. ELA increases the risk of intrapartum maternal fever; the latter may be harmful to neonatal outcomes. The use of ELA may increase birth injury by increasing instrumental delivery, although long-term adverse events are rare. On the other hand, ELA may reduce maternal depression and, thus, produce favorable effects on neurocognitive development in childhood; but evidences are still lacking in this aspect. ELA may produce both favorable and unfavorable effects on neonates and children. These effects should be discussed with parturient women before making decisions. The potential harmful effects should be carefully managed. The overall impacts of ELA on neonatal and children's outcomes need to be studied further.http://journals.lww.com/10.1097/CM9.0000000000000900 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Zhi-Hua Liu Dong-Xin Wang Li-Shao Guo |
spellingShingle |
Zhi-Hua Liu Dong-Xin Wang Li-Shao Guo Potential impact of epidural labor analgesia on the outcomes of neonates and children Chinese Medical Journal |
author_facet |
Zhi-Hua Liu Dong-Xin Wang Li-Shao Guo |
author_sort |
Zhi-Hua Liu |
title |
Potential impact of epidural labor analgesia on the outcomes of neonates and children |
title_short |
Potential impact of epidural labor analgesia on the outcomes of neonates and children |
title_full |
Potential impact of epidural labor analgesia on the outcomes of neonates and children |
title_fullStr |
Potential impact of epidural labor analgesia on the outcomes of neonates and children |
title_full_unstemmed |
Potential impact of epidural labor analgesia on the outcomes of neonates and children |
title_sort |
potential impact of epidural labor analgesia on the outcomes of neonates and children |
publisher |
Wolters Kluwer |
series |
Chinese Medical Journal |
issn |
0366-6999 2542-5641 |
publishDate |
2020-10-01 |
description |
Abstract. This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including “ELA,” “ELA and neonatal outcomes,” “ELA and children's development,” and “ELA and children's neurocognitive development” were used to search articles published in PubMed database up to October 2019. Original articles and reviews regarding potential influences of ELA on neonates and children were identified. Relevant references of the selected articles were also screened. The anesthetics used during ELA can be absorbed, enter the fetus, and produce neonatal depression; however, these effects are less severe than those during systematic opioid analgesia. The impact of anesthetic exposure during ELA on children's neurodevelopment has not been fully studied, but would be mild if any. ELA increases the risk of intrapartum maternal fever; the latter may be harmful to neonatal outcomes. The use of ELA may increase birth injury by increasing instrumental delivery, although long-term adverse events are rare. On the other hand, ELA may reduce maternal depression and, thus, produce favorable effects on neurocognitive development in childhood; but evidences are still lacking in this aspect. ELA may produce both favorable and unfavorable effects on neonates and children. These effects should be discussed with parturient women before making decisions. The potential harmful effects should be carefully managed. The overall impacts of ELA on neonatal and children's outcomes need to be studied further. |
url |
http://journals.lww.com/10.1097/CM9.0000000000000900 |
work_keys_str_mv |
AT zhihualiu potentialimpactofepidurallaboranalgesiaontheoutcomesofneonatesandchildren AT dongxinwang potentialimpactofepidurallaboranalgesiaontheoutcomesofneonatesandchildren AT lishaoguo potentialimpactofepidurallaboranalgesiaontheoutcomesofneonatesandchildren |
_version_ |
1724407737322831872 |