Active invasion of oral and aortic tissues by Porphyromonas gingivalis in mice causally links periodontitis and atherosclerosis.

Atherosclerotic vascular disease is a leading cause of myocardial infarction and cerebrovascular accident, and independent associations with periodontal disease (PD) are reported. PD is caused by polymicrobial infections and aggressive immune responses. Genomic DNA of Porphyromonas gingivalis, the b...

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Main Authors: Irina M Velsko, Sasanka S Chukkapalli, Mercedes F Rivera, Ju-Youn Lee, Hao Chen, Donghang Zheng, Indraneel Bhattacharyya, Pandu R Gangula, Alexandra R Lucas, Lakshmyya Kesavalu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4024021?pdf=render