PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin
Background The success of new targeted cancer therapies has been dependent on the identification of tumor-specific antigens. Podocalyxin (Podxl) is upregulated on tumors with high metastatic index and its presence is associated with poor outcome, thus emerging as an important prognostic and theragno...
Main Authors: | Blake Gilks, Martin Köbel, Diana Canals Hernaez, Michael R Hughes, Pamela Dean, Peter Bergqvist, Ismael Samudio, Ola Blixt, Katharina Wiedemeyer, Yicong Li, Chris Bond, Eric Cruz, Calvin D Roskelley, Kelly M McNagny |
---|---|
Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-07-01
|
Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/8/2/e001128.full |
Similar Items
-
The CD34-related molecule podocalyxin is a potent inducer of microvillus formation.
by: Julie S Nielsen, et al.
Published: (2007-02-01) -
Determination of critical epitope of PcMab-47 against human podocalyxin
by: Shunsuke Itai, et al.
Published: (2018-07-01) -
Podocalyxin regulates murine lung vascular permeability by altering endothelial cell adhesion.
by: Erin J Debruin, et al.
Published: (2014-01-01) -
Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation.
by: Nathalia Vitureira, et al.
Published: (2010-08-01) -
Analysis of muscle tone distribution in premature babies based on PodoBaby podoscope examination
by: Stępowska Jolanta, et al.
Published: (2017-12-01)