Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish
Mechanical forces play a crucial role during morphogenesis, but how these are sensed and transduced in vivo is not fully understood. Here the authors apply a FRET tension sensor to live zebrafish and study changes in VE-cadherin tension at endothelial cell-cell junctions during arterial maturation.
Bibliographic Details
Main Authors: |
Anne Karine Lagendijk,
Guillermo A. Gomez,
Sungmin Baek,
Daniel Hesselson,
William E. Hughes,
Scott Paterson,
Daniel E. Conway,
Heinz-Georg Belting,
Markus Affolter,
Kelly A. Smith,
Martin A. Schwartz,
Alpha S. Yap,
Benjamin M. Hogan |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2017-11-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-017-01325-6
|