The status of cryptococcosis in Latin America
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients...
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Instituto Oswaldo Cruz, Ministério da Saúde
2018-04-01
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doaj-060279db4a3a4db18044492dbe3393a82020-11-25T00:13:58ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.1678-80602018-04-01113710.1590/0074-02760170554S0074-02762018000700203The status of cryptococcosis in Latin AmericaCarolina FiracativeJairo LizarazoMaría Teresa Illnait-ZaragozíElizabeth CastañedaCryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients with HIV, while C. gattii generally affects otherwise healthy individuals. In this region, cryptococcal meningitis is the most common presentation, with amphotericin B and fluconazole being the antifungal drugs of choice. Avian droppings are the predominant environmental reservoir of C. neoformans, while C. gattii is associated with several arboreal species. Importantly, C. gattii has a high prevalence in Latin America and has been proposed to be the likely origin of some C. gattii populations in North America. Thus, in the recent years, significant progress has been made with the study of the basic biology and laboratory identification of cryptococcal strains, in understanding their ecology, population genetics, host-pathogen interactions, and the clinical epidemiology of this important mycosis in Latin America.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000700203&lng=en&tlng=enCryptococcus neoformansCryptococcus gattiiLatin Americacryptococcosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Carolina Firacative Jairo Lizarazo María Teresa Illnait-Zaragozí Elizabeth Castañeda |
spellingShingle |
Carolina Firacative Jairo Lizarazo María Teresa Illnait-Zaragozí Elizabeth Castañeda The status of cryptococcosis in Latin America Memórias do Instituto Oswaldo Cruz. Cryptococcus neoformans Cryptococcus gattii Latin America cryptococcosis |
author_facet |
Carolina Firacative Jairo Lizarazo María Teresa Illnait-Zaragozí Elizabeth Castañeda |
author_sort |
Carolina Firacative |
title |
The status of cryptococcosis in Latin America |
title_short |
The status of cryptococcosis in Latin America |
title_full |
The status of cryptococcosis in Latin America |
title_fullStr |
The status of cryptococcosis in Latin America |
title_full_unstemmed |
The status of cryptococcosis in Latin America |
title_sort |
status of cryptococcosis in latin america |
publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
series |
Memórias do Instituto Oswaldo Cruz. |
issn |
1678-8060 |
publishDate |
2018-04-01 |
description |
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients with HIV, while C. gattii generally affects otherwise healthy individuals. In this region, cryptococcal meningitis is the most common presentation, with amphotericin B and fluconazole being the antifungal drugs of choice. Avian droppings are the predominant environmental reservoir of C. neoformans, while C. gattii is associated with several arboreal species. Importantly, C. gattii has a high prevalence in Latin America and has been proposed to be the likely origin of some C. gattii populations in North America. Thus, in the recent years, significant progress has been made with the study of the basic biology and laboratory identification of cryptococcal strains, in understanding their ecology, population genetics, host-pathogen interactions, and the clinical epidemiology of this important mycosis in Latin America. |
topic |
Cryptococcus neoformans Cryptococcus gattii Latin America cryptococcosis |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000700203&lng=en&tlng=en |
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