High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS
Menghui Li,1,2,* Lijuan Wei,1,* Fangxuan Li,1 Yanyan Kan,1 Xiaofeng Liang,1 Huan Zhang,1 Juntian Liu1,2 1Cancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People’s Republic of China; 2National Clinical Research Center for Cancer, Key Laboratory of...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Dove Medical Press
2021-01-01
|
Series: | Cancer Management and Research |
Subjects: | |
Online Access: | https://www.dovepress.com/high-risk-thyroid-nodule-discrimination-and-management-by-modified-ti--peer-reviewed-article-CMAR |
id |
doaj-0604226b58ef4411a8821c5afd49d714 |
---|---|
record_format |
Article |
spelling |
doaj-0604226b58ef4411a8821c5afd49d7142021-01-12T22:45:00ZengDove Medical PressCancer Management and Research1179-13222021-01-01Volume 1322523461053High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADSLi MWei LLi FKan YLiang XZhang HLiu JMenghui Li,1,2,* Lijuan Wei,1,* Fangxuan Li,1 Yanyan Kan,1 Xiaofeng Liang,1 Huan Zhang,1 Juntian Liu1,2 1Cancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People’s Republic of China; 2National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Menghui Li; Juntian LiuTianjin Medical University Cancer Institute and Hospital, Huanhuxi Road, Hexi District, Tianjin 300060, People’s Republic of ChinaTel/Fax +86 22-23340123Email limenghui820117@163.com : ljt641024@163.comObjective: Thyroid cancer is the most common primary malignant disorder of the thyroid. We aimed to illustrate the modified TI-RADS report system for differentiating malignant thyroid nodules from benign ones, and especially its role in the management of high risk nodules.Methods: In this retrospective study, 5,162 healthy individuals who underwent thyroid ultrasound according to modified TI-RADS from January 2014 to December 2014 were enrolled and followed up during the whole 5 years, and the medical data were investigated and reviewed.Results: The total detection rate of thyroid nodules was 39.40%. The total detection rate of thyroid cancer was 0.66%. Most thyroid cancers were single-shot, located at unilateral, at early clinical stages, without lymph node metastases, and with low recurrence risk. All patients had thyroid papillary carcinoma, except one thyroid medullary carcinoma. Based on modified TI-RADS classification, at the end of 5 years follow-up, more changes of thyroid nodules grade status were observed in grades 4a and above. The higher the grade status, the more malignant advances were occurred. The modified TI-RADS report system played an instructional role in adding medical treatment choice and decision for clinicians.Conclusion: The modified TI-RADS report system plays an important role in thyroid benign and malignant nodule identification and management.Keywords: thyroid cancer, thyroid nodules, high-risk nodules, thyroid ultrasound, TI-RADS report systemhttps://www.dovepress.com/high-risk-thyroid-nodule-discrimination-and-management-by-modified-ti--peer-reviewed-article-CMARthyroid cancerthyroid noduleshigh-risk nodulesthyroid ultrasoundti-rads report system |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Li M Wei L Li F Kan Y Liang X Zhang H Liu J |
spellingShingle |
Li M Wei L Li F Kan Y Liang X Zhang H Liu J High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS Cancer Management and Research thyroid cancer thyroid nodules high-risk nodules thyroid ultrasound ti-rads report system |
author_facet |
Li M Wei L Li F Kan Y Liang X Zhang H Liu J |
author_sort |
Li M |
title |
High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS |
title_short |
High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS |
title_full |
High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS |
title_fullStr |
High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS |
title_full_unstemmed |
High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS |
title_sort |
high risk thyroid nodule discrimination and management by modified ti-rads |
publisher |
Dove Medical Press |
series |
Cancer Management and Research |
issn |
1179-1322 |
publishDate |
2021-01-01 |
description |
Menghui Li,1,2,* Lijuan Wei,1,* Fangxuan Li,1 Yanyan Kan,1 Xiaofeng Liang,1 Huan Zhang,1 Juntian Liu1,2 1Cancer Prevention Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin, People’s Republic of China; 2National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, People’s Republic of China*These authors contributed equally to this workCorrespondence: Menghui Li; Juntian LiuTianjin Medical University Cancer Institute and Hospital, Huanhuxi Road, Hexi District, Tianjin 300060, People’s Republic of ChinaTel/Fax +86 22-23340123Email limenghui820117@163.com : ljt641024@163.comObjective: Thyroid cancer is the most common primary malignant disorder of the thyroid. We aimed to illustrate the modified TI-RADS report system for differentiating malignant thyroid nodules from benign ones, and especially its role in the management of high risk nodules.Methods: In this retrospective study, 5,162 healthy individuals who underwent thyroid ultrasound according to modified TI-RADS from January 2014 to December 2014 were enrolled and followed up during the whole 5 years, and the medical data were investigated and reviewed.Results: The total detection rate of thyroid nodules was 39.40%. The total detection rate of thyroid cancer was 0.66%. Most thyroid cancers were single-shot, located at unilateral, at early clinical stages, without lymph node metastases, and with low recurrence risk. All patients had thyroid papillary carcinoma, except one thyroid medullary carcinoma. Based on modified TI-RADS classification, at the end of 5 years follow-up, more changes of thyroid nodules grade status were observed in grades 4a and above. The higher the grade status, the more malignant advances were occurred. The modified TI-RADS report system played an instructional role in adding medical treatment choice and decision for clinicians.Conclusion: The modified TI-RADS report system plays an important role in thyroid benign and malignant nodule identification and management.Keywords: thyroid cancer, thyroid nodules, high-risk nodules, thyroid ultrasound, TI-RADS report system |
topic |
thyroid cancer thyroid nodules high-risk nodules thyroid ultrasound ti-rads report system |
url |
https://www.dovepress.com/high-risk-thyroid-nodule-discrimination-and-management-by-modified-ti--peer-reviewed-article-CMAR |
work_keys_str_mv |
AT lim highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT weil highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT lif highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT kany highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT liangx highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT zhangh highriskthyroidnodulediscriminationandmanagementbymodifiedtirads AT liuj highriskthyroidnodulediscriminationandmanagementbymodifiedtirads |
_version_ |
1724339832859131904 |