Advantages of using graph databases to explore chromatin conformation capture experiments
Abstract Background High-throughput sequencing Chromosome Conformation Capture (Hi-C) allows the study of DNA interactions and 3D chromosome folding at the genome-wide scale. Usually, these data are represented as matrices describing the binary contacts among the different chromosome regions. On the...
Main Authors: | Daniele D’Agostino, Pietro Liò, Marco Aldinucci, Ivan Merelli |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-04-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-020-03937-0 |
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