Scutellarin Enhances Antitumor Effects and Attenuates the Toxicity of Bleomycin in H22 Ascites Tumor-Bearing Mice

Scutellarin Enhances Antitumor Effects and Attenuates the Toxicity of Bleomycin in H22 Ascites Tumor-Bearing Mice

Bleomycin (BLM) is a broad spectrum anti-tumor drug and inducing pulmonary fibrosis. As an anti-tumor drug without immunosuppression, it is urgent to find a drug that reduces the side effects of BLM. Scutellarin (SCU), a flavone extracted from Erigeron breviscapus (Vant.) Hand-Mazz, has anti-inflamm...

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Bibliographic Details
Main Authors: Juan Nie, Hong-Mei Yang, Chao-Yue Sun, Yan-Lu Liu, Jian-Yi Zhuo, Zhen-Biao Zhang, Xiao-Ping Lai, Zi-Ren Su, Yu-Cui Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
scutellarin
bleomycin
anti-tumor
pulmonary fibrosis
combined administration
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00615/full

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