Lipid-polymer nanoparticles with CD133 aptamers for targeted delivery of all-trans retinoic acid to osteosarcoma initiating cells

Lipid-polymer nanoparticles with CD133 aptamers for targeted delivery of all-trans retinoic acid to osteosarcoma initiating cells

Osteosarcoma, a common type of bone cancer in children, and represents an aggressive and fetal cancer worldwide. Osteosarcoma initiating cells are considered to be a subpopulation of cancer cells which contribute to the progression, recurrence, metastasis and multi-drug resistance of osteosarcoma. C...

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Bibliographic Details
Main Authors:	Keke Gui, Xinchao Zhang, Fangyi Chen, Zhe Ge, Shichao Zhang, Xiaoxia Qi, Jing Sun, Zuochong Yu
Format:	Article
Language:	English
Published:	Elsevier 2019-03-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Nanoparticles Cancer stem cells Osteosarcoma All-trans retinoic acid CD133
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332218340022

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