Mycobacterium tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells.
The survival and persistence of Mycobacterium tuberculosis depends on its capacity to manipulate multiple host defense pathways, including the ability to actively inhibit the death by apoptosis of infected host cells. The genetic basis for this anti-apoptotic activity and its implication for mycobac...
Main Authors: | Kamalakannan Velmurugan, Bing Chen, Jessica L Miller, Sharon Azogue, Serdar Gurses, Tsungda Hsu, Michael Glickman, William R Jacobs, Steven A Porcelli, Volker Briken |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC1924871?pdf=render |
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