Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature

An unusual cause of upper gastrointestinal bleeding is described in a previously healthy 45-year-old man who was admitted to hospital with weakness and fatigue, and had experienced an episode of melena two days before admission. His medical and surgical history was unremarkable. Upon admission to ho...

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Main Authors:	David R Stolpman, Gordon C Hunt, Brett Sheppard, Hahn Huang, Deepak V Gopal
Format:	Article
Language:	English
Published:	Hindawi Limited 2002-01-01
Series:	Canadian Journal of Gastroenterology
Online Access:	http://dx.doi.org/10.1155/2002/797934

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spelling	doaj-0638ad97ae7e441aa1c9ac0db70277442020-11-24T23:59:50ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79002002-01-0116530931310.1155/2002/797934Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the LiteratureDavid R Stolpman0Gordon C Hunt1Brett Sheppard2Hahn Huang3Deepak V Gopal4Division of Gastroenterology, Oregon Health Sciences University, Portland, Oregon, USADivision of Gastroenterology, Oregon Health Sciences University, Portland, Oregon, USADepartment of Surgery, Oregon Health Sciences University, Portland, Oregon, USADepartment of Pathology, Oregon Health Sciences University, Portland, Oregon, USADivision of Gastroenterology, Oregon Health Sciences University, Portland, Oregon, USAAn unusual cause of upper gastrointestinal bleeding is described in a previously healthy 45-year-old man who was admitted to hospital with weakness and fatigue, and had experienced an episode of melena two days before admission. His medical and surgical history was unremarkable. Upon admission to hospital, he showed evidence of iron-deficiency anemia, with a hemoglobin concentration of 61 g/L (normal range 135 to 175 g/L), a mean corpuscular volume of 73 fL (normal range 85.0 to 95.0 fL) and a ferritin concentration of 1.0 µg/L (normal range in males 15 to 400 µg/L). Upper gastrointestinal endoscopy revealed a 3.5 cm ulcerated submucosal mass in the third portion of the duodenum, for which mucosal biopsies were nondiagnostic. A subsequent endoscopic ultrasound revealed a 2.7×4.0 cm hyperechoic, cystic, submucosal tumour in the third portion of the duodenum. Endoscopic ultrasound-guided fine needle aspiration revealed no malignant cells. The patient eventually underwent a resection of the third portion of his duodenum. Surgical pathology revealed that this tumour was a Brunner’s gland hamartoma, 4.5 cm in its greatest dimension.http://dx.doi.org/10.1155/2002/797934
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	David R Stolpman Gordon C Hunt Brett Sheppard Hahn Huang Deepak V Gopal
spellingShingle	David R Stolpman Gordon C Hunt Brett Sheppard Hahn Huang Deepak V Gopal Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature Canadian Journal of Gastroenterology
author_facet	David R Stolpman Gordon C Hunt Brett Sheppard Hahn Huang Deepak V Gopal
author_sort	David R Stolpman
title	Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature
title_short	Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature
title_full	Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature
title_fullStr	Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature
title_full_unstemmed	Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature
title_sort	brunner’s gland hamartoma: a rare cause of gastrointestinal bleeding – case report and review of the literature
publisher	Hindawi Limited
series	Canadian Journal of Gastroenterology
issn	0835-7900
publishDate	2002-01-01
description	An unusual cause of upper gastrointestinal bleeding is described in a previously healthy 45-year-old man who was admitted to hospital with weakness and fatigue, and had experienced an episode of melena two days before admission. His medical and surgical history was unremarkable. Upon admission to hospital, he showed evidence of iron-deficiency anemia, with a hemoglobin concentration of 61 g/L (normal range 135 to 175 g/L), a mean corpuscular volume of 73 fL (normal range 85.0 to 95.0 fL) and a ferritin concentration of 1.0 µg/L (normal range in males 15 to 400 µg/L). Upper gastrointestinal endoscopy revealed a 3.5 cm ulcerated submucosal mass in the third portion of the duodenum, for which mucosal biopsies were nondiagnostic. A subsequent endoscopic ultrasound revealed a 2.7×4.0 cm hyperechoic, cystic, submucosal tumour in the third portion of the duodenum. Endoscopic ultrasound-guided fine needle aspiration revealed no malignant cells. The patient eventually underwent a resection of the third portion of his duodenum. Surgical pathology revealed that this tumour was a Brunner’s gland hamartoma, 4.5 cm in its greatest dimension.
url	http://dx.doi.org/10.1155/2002/797934
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Brunner’s Gland Hamartoma: A Rare Cause of Gastrointestinal Bleeding – Case Report and Review of the Literature

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