Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation
Long noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection.
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2016-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms11730 |
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doaj-0658e7370fef4de8af787a5e70268d4a2021-05-11T11:05:49ZengNature Publishing GroupNature Communications2041-17232016-06-017111010.1038/ncomms11730Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradationJun Li0Cancan Chen1Xiancai Ma2Guannan Geng3Bingfeng Liu4Yijun Zhang5Shaoyang Zhang6Fudi Zhong7Chao Liu8Yue Yin9Weiping Cai10Hui Zhang11Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityDepartment of Infectious Diseases, Guangzhou 8th People’s HospitalInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen UniversityLong noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection.https://doi.org/10.1038/ncomms11730 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang |
spellingShingle |
Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation Nature Communications |
author_facet |
Jun Li Cancan Chen Xiancai Ma Guannan Geng Bingfeng Liu Yijun Zhang Shaoyang Zhang Fudi Zhong Chao Liu Yue Yin Weiping Cai Hui Zhang |
author_sort |
Jun Li |
title |
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
title_short |
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
title_full |
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
title_fullStr |
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
title_full_unstemmed |
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation |
title_sort |
long noncoding rna nron contributes to hiv-1 latency by specifically inducing tat protein degradation |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2016-06-01 |
description |
Long noncoding RNAs have a wide range of physiological functions, though their role in viral infection and latency is poorly understood. Here the authors show a lncRNA NRON can induce degradation of HIV-1 protein Tat, potentially contributing to latent infection. |
url |
https://doi.org/10.1038/ncomms11730 |
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