Polymorphism in Integrin ITGA2 is Associated with Ischemic Stroke and Altered Serum Cholesterol in Chinese Individuals

Polymorphism in Integrin ITGA2 is Associated with Ischemic Stroke and Altered Serum Cholesterol in Chinese Individuals

Background: Recent studies have reported contrasting results regarding the association of polymorphisms in two integrin genes, ITGA2 and ITGB3, with ischemic stroke. Aims: The present study aimed to investigate the correlation between the ITGA2 C807T and ITGB3 T176C polymorphic loci with ischemic...

Full description

Bibliographic Details
Main Authors:	Jian-Xia Lu, Zhong-Qian Lu, Wan-Xiang Wang, Shao-lan Zhang, Juan Zhi, Zheng-Ping Chen
Format:	Article
Language:	English
Published:	Galenos Publishing House 2014-03-01
Series:	Balkan Medical Journal
Subjects:	Integrin α2 Integrin β3 ischemic stroke Gene polymorphism plasma lipid
Online Access:	http://balkanmedicaljournal.org/text.php?lang=en&id=339

Similar Items

The Inflammatory Response After Ischemic Stroke: Targeting β2 and β1 Integrins
by: Danielle N. Edwards, et al.
Published: (2019-05-01)

INTEGRIN α5β1 AS A NOVEL TARGET WITH THE SMALL PEPTIDE, ATN-161, IN THE TREATMENT OF ISCHEMIC STROKE
by: Edwards, Danielle Nichele
Published: (2019)

Integrin α5/ITGA5 Promotes The Proliferation, Migration, Invasion And Progression Of Oral Squamous Carcinoma By Epithelial–Mesenchymal Transition
by: Deng Y, et al.
Published: (2019-11-01)

Collagen Assembly at the Cell Surface: Dogmas Revisited
by: Moses Musiime, et al.
Published: (2021-03-01)

Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates
by: Ivana Samaržija, et al.
Published: (2020-07-01)

The effect of divalent metal cations on the αv integrin binding site is ligand and integrin specific
by: Eleanor R. Hall, et al.
Published: (2019-02-01)

LXW7 ameliorates focal cerebral ischemia injury and attenuates inflammatory responses in activated microglia in rats
by: T. Fang, et al.
Published: (2016-08-01)

The Activation and Regulation of β2 Integrins in Phagocytes and Phagocytosis
by: Hao Sun, et al.
Published: (2021-03-01)

Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells
by: Romana Dolinschek, et al.
Published: (2021-02-01)

Sex differences in the development of vascular and renal lesions in mice with a simultaneous deficiency of Apoe and the integrin chain Itga8
by: Ines Marek, et al.
Published: (2017-05-01)

Addressing the Compartmentalization of Specific Integrin Heterodimers in Mouse Sperm
by: Michaela Frolikova, et al.
Published: (2019-02-01)

Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts
by: Francesca Aglialoro, et al.
Published: (2020-07-01)

Genetic Polymorphism TNFα -308G>A and Ischemic Stroke in Northern Romania
by: Petrișor Felicia, et al.
Published: (2013-04-01)

Expressions of type I collagen, α2 integrin and β1 integrin in sclera of guinea pig with defocus myopia and inhibitory effects of bFGF on the formation of myopia
by: Xiao-Dan Tian
Published: (2013-02-01)

PROAGIO (A PROTEIN DESIGNED TO TARGET INTEGRIN αVβ3)
by: Turaga, Ravi C
Published: (2017)

Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke
by: Jian-xia Lu, et al.
Published: (2013-06-01)

Correlation between interleukin-18 promoter -607C/A polymorphism and susceptibility to ischemic stroke
by: Jian-xia Lu, et al.
Published: (2013-01-01)

Integrins in cardiac hypertrophy: lessons learned from culture systems
by: Natalya Bildyug
Published: (2021-10-01)

Study of associations of polymorphic variants of lipid metabolism genes and angiogenesis with first ischemic stroke
by: Veronika N. Shishkova, et al.
Published: (2019-02-01)

Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cells
by: Hyun Min Lee, et al.
Published: (2020-06-01)

Laminin Binding α6β1 Integrin Regulation in Aggressive Cancer Cells and Tissue
by: Sandoval Rubenstein, Cynthia Priscilla, et al.
Published: (2017)

Expression and function of the 1B integrin subunit in human keratinocytes
by: Kee, Wai Jing
Published: (1999)

Involvement of Integrin-Activating Peptides Derived from Tenascin-C in Cancer Aggression and New Anticancer Strategy Using the Fibronectin-Derived Integrin-Inactivating Peptide
by: Motomichi Fujita, et al.
Published: (2020-07-01)

MYC Regulates α6 Integrin Subunit Expression and Splicing Under Its Pro-Proliferative ITGA6A Form in Colorectal Cancer Cells
by: Jean-François Groulx, et al.
Published: (2018-02-01)

Mechanisms of Integrin Signal Transduction
by: Stefansson, Anne
Published: (2007)

A Role for Integrin-linked Kinase In Oligodendrocyte Mediated Myelination of the Central Nervous System
by: Michalski, John-Paul
Published: (2014)

Structural Studies of Talin-mediated Integrin Activation
by: Bakhautdin, Esen
Published: (2009)

Ndr2 Kinase Controls Neurite Outgrowth and Dendritic Branching Through α1 Integrin Expression
by: Yunus E. Demiray, et al.
Published: (2018-03-01)

ASSESSMENT OF THE POLYMORPHIC GENES VARIANTS OF THE LIPID AND CARBOHYDRATE METABOLISM, VASCULAR INFLAMMATION AND NEUROTRANSMITTER SYSTEM IN THE FIRST ISCHEMIC STROKE
by: V. N. Shishkova, et al.
Published: (2017-10-01)

The role of integrins on megakaryocyte development and function
by: Yang, Xiaosheng
Published: (2021)

Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage
by: Shijun He, et al.
Published: (2019-01-01)

Thyroxine Induces Acute Relaxation of Rat Skeletal Muscle Arteries via Integrin αvβ3, ERK1/2 and Integrin-Linked Kinase
by: Ekaterina K. Selivanova, et al.
Published: (2021-09-01)

The small-molecule protein ligand interface stabiliser E7820 induces differential cell line specific responses of integrin α2 expression
by: Michael David Hülskamp, et al.
Published: (2021-05-01)

Structural and Functional Aspects of β1 Integrin Signalling
by: Nilsson, Stina
Published: (2006)

The Development of Integrin Alpha-8 Deficient Lungs Shows Reduced and Altered Branching and a Correction of the Phenotype During Alveolarization
by: Tiziana P. Cremona, et al.
Published: (2020-12-01)

16 kDa vasoinhibin binds to integrin alpha5 beta1 on endothelial cells to induce apoptosis
by: Kazunori Morohoshi, et al.
Published: (2018-04-01)

Chemokines and the signaling modules regulating integrin affinity
by: Alessio eMontresor, et al.
Published: (2012-05-01)

T Cell Integrin Overexpression as a Model of Murine Autoimmunity
by: Yung Raymond L., et al.
Published: (2003-01-01)

The Role of Matrix Metalloproteinase Polymorphisms in Ischemic Stroke
by: Jason J. Chang, et al.
Published: (2016-08-01)

Integrin and gene network analysis reveals that ITGA5 and ITGB1 are prognostic in non-small-cell lung cancer
by: Zheng WQ, et al.
Published: (2016-04-01)