Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus
Different solvents were used for sumac extractions to find different active compounds in each fraction, and these fractions were tested on Staphylococcus aureus (which isolated from soft white cheese), the (MIC) minimum inhibitory concentration of each fraction were measured then sub-inhibitory conc...
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Journal of Pure and Applied Microbiology
2019-12-01
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doaj-06b7f4ef514343d9bb8da4f8f6121c2a2021-10-02T17:24:19ZengJournal of Pure and Applied MicrobiologyJournal of Pure and Applied Microbiology0973-75102581-690X2019-12-011342397240410.22207/JPAM.13.4.56Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureusAbdulilah Saleh Ismaeil0Fraidoon A. Saleh1Biology Department, Science College, Salahaddin University, Erbil, Kurdistan, Iraq.Biology Department, Science College, Salahaddin University, Erbil, Kurdistan, Iraq.Different solvents were used for sumac extractions to find different active compounds in each fraction, and these fractions were tested on Staphylococcus aureus (which isolated from soft white cheese), the (MIC) minimum inhibitory concentration of each fraction were measured then sub-inhibitory concentration (SIC) was used. We found that all fractions can inhibit quorum sensing in Staphylococcus aureus in a different ratio. By using Real-time PCR found that the different sumac fractions can inhibit the expression of tested genes (Sea, Seb, AgrA, RNAIII, and Hla). Furthermore, most sumac extracted fractions have the ability to decreasing biofilm and growth curve in Staphylococcus aureus significantly, while other fractions decreased them non-significantly. https://microbiologyjournal.org/sumac-rhus-coriaria-l-as-quorum-sensing-inhibitors-in-staphylococcus-aureus/staphylococcus aureussumac extractquorum sensing inhibitorbiofilmgrowth curve |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Abdulilah Saleh Ismaeil Fraidoon A. Saleh |
spellingShingle |
Abdulilah Saleh Ismaeil Fraidoon A. Saleh Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus Journal of Pure and Applied Microbiology staphylococcus aureus sumac extract quorum sensing inhibitor biofilm growth curve |
author_facet |
Abdulilah Saleh Ismaeil Fraidoon A. Saleh |
author_sort |
Abdulilah Saleh Ismaeil |
title |
Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus |
title_short |
Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus |
title_full |
Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus |
title_fullStr |
Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus |
title_full_unstemmed |
Sumac (Rhus coriaria L) as Quorum Sensing Inhibitors in Staphylococcus aureus |
title_sort |
sumac (rhus coriaria l) as quorum sensing inhibitors in staphylococcus aureus |
publisher |
Journal of Pure and Applied Microbiology |
series |
Journal of Pure and Applied Microbiology |
issn |
0973-7510 2581-690X |
publishDate |
2019-12-01 |
description |
Different solvents were used for sumac extractions to find different active compounds in each fraction, and these fractions were tested on Staphylococcus aureus (which isolated from soft white cheese), the (MIC) minimum inhibitory concentration of each fraction were measured then sub-inhibitory concentration (SIC) was used. We found that all fractions can inhibit quorum sensing in Staphylococcus aureus in a different ratio. By using Real-time PCR found that the different sumac fractions can inhibit the expression of tested genes (Sea, Seb, AgrA, RNAIII, and Hla). Furthermore, most sumac extracted fractions have the ability to decreasing biofilm and growth curve in Staphylococcus aureus significantly, while other fractions decreased them non-significantly.
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topic |
staphylococcus aureus sumac extract quorum sensing inhibitor biofilm growth curve |
url |
https://microbiologyjournal.org/sumac-rhus-coriaria-l-as-quorum-sensing-inhibitors-in-staphylococcus-aureus/ |
work_keys_str_mv |
AT abdulilahsalehismaeil sumacrhuscoriarialasquorumsensinginhibitorsinstaphylococcusaureus AT fraidoonasaleh sumacrhuscoriarialasquorumsensinginhibitorsinstaphylococcusaureus |
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1716851866446331904 |