Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy

Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy

Background. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-b...

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Bibliographic Details
Main Authors: S. Murray Yule, Roderick Skinner, Martin W. English, Mike Cole, Andrew D. J. Pearson, Helen H. Lucraft, Alan W. Craft
Format: Article
Language:English
Published: Hindawi Limited 1998-01-01
Series:Sarcoma
Online Access:http://dx.doi.org/10.1080/13577149877939
Description
Summary:Background. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-based regimen with local therapy directed only to children who failed to achieve a complete response to initial chemotherapy.
ISSN:1357-714X
1369-1643

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