Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy

Background. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-b...

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Main Authors:	S. Murray Yule, Roderick Skinner, Martin W. English, Mike Cole, Andrew D. J. Pearson, Helen H. Lucraft, Alan W. Craft
Format:	Article
Language:	English
Published:	Hindawi Limited 1998-01-01
Series:	Sarcoma
Online Access:	http://dx.doi.org/10.1080/13577149877939

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spelling	doaj-06c00972d753443580d852731bd1d6f12020-11-24T22:30:07ZengHindawi LimitedSarcoma1357-714X1369-16431998-01-0123-417117710.1080/13577149877939Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local TherapyS. Murray Yule0Roderick Skinner1Martin W. English2Mike Cole3Andrew D. J. Pearson4Helen H. Lucraft5Alan W. Craft6Department of Child Health, The University of Newcastle upon Tyne, UKDepartment of Child Health, The University of Newcastle upon Tyne, UKDepartment of Child Health, The University of Newcastle upon Tyne, UKDepartment of Child Health, The University of Newcastle upon Tyne, UKDepartment of Child Health, The University of Newcastle upon Tyne, UKThe Northern Centre for Cancer Treatment, Newcastle General Hospital, Newcastle upon Tyne, UKDepartment of Child Health, The University of Newcastle upon Tyne, UKBackground. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-based regimen with local therapy directed only to children who failed to achieve a complete response to initial chemotherapy.http://dx.doi.org/10.1080/13577149877939
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	S. Murray Yule Roderick Skinner Martin W. English Mike Cole Andrew D. J. Pearson Helen H. Lucraft Alan W. Craft
spellingShingle	S. Murray Yule Roderick Skinner Martin W. English Mike Cole Andrew D. J. Pearson Helen H. Lucraft Alan W. Craft Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy Sarcoma
author_facet	S. Murray Yule Roderick Skinner Martin W. English Mike Cole Andrew D. J. Pearson Helen H. Lucraft Alan W. Craft
author_sort	S. Murray Yule
title	Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
title_short	Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
title_full	Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
title_fullStr	Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
title_full_unstemmed	Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy
title_sort	outcome and toxicity of an ifosfamide-based soft tissue sarcoma treatment protocol in children. the importance of local therapy
publisher	Hindawi Limited
series	Sarcoma
issn	1357-714X 1369-1643
publishDate	1998-01-01
description	Background. Although the survival of children with soft tissue sarcoma (STS) has improved considerably, the outcome of patients with metastatic disease, and those with primary tumours of the extremities or parameningeal sites remains disappointing. We describe the clinical outcome of an ifosfamide-based regimen with local therapy directed only to children who failed to achieve a complete response to initial chemotherapy.
url	http://dx.doi.org/10.1080/13577149877939
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Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy

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