Effect of Geometrical Structure, Drying, and Synthetic Method on Aminated Chitosan-Coated Magnetic Nanoparticles Utility for HSA Effective Immobilization

Effect of Geometrical Structure, Drying, and Synthetic Method on Aminated Chitosan-Coated Magnetic Nanoparticles Utility for HSA Effective Immobilization

Human serum albumin (HSA) is one of the most frequently immobilized proteins on the surface of carriers, including magnetic nanoparticles. This is because the drug−HSA interaction study is one of the basic pharmacokinetic parameters determined for drugs. In spite of many works describing t...

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Bibliographic Details
Main Authors: Marta Ziegler-Borowska, Kinga Mylkie, Mariana Kozlowska, Pawel Nowak, Dorota Chelminiak-Dudkiewicz, Anna Kozakiewicz, Anna Ilnicka, Anna Kaczmarek-Kedziera
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
aminated chitosan
magnetic nanoparticles
HSA
protein immobilization
molecular dynamics simulations
solvent-free amination
Online Access:https://www.mdpi.com/1420-3049/24/10/1925

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