The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues
Pelvic radiation for cancer therapy can damage a variety of normal tissues. In this study, we demonstrate that radiation causes acute changes to pelvic fibroblasts such as the transformation to myofibroblasts and the induction of senescence, which persist months after radiation. The addition of the...
Main Authors: | Shashank Shrishrimal, Elizabeth A. Kosmacek, Arpita Chatterjee, McDonald J. Tyson, Rebecca E. Oberley-Deegan |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-11-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/6/4/87 |
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