Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial
"AIM: To compare visual prognoses and postoperative adverse events of congenital cataract surgery performed at different times and using different surgical approaches. METHODS: In this prospective, randomized controlled trial, we recruited congenital cataract patients aged 3mo or younger befor...
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doaj-06f17b16b77b434e8d133b9a379cee592020-11-24T21:15:31ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982017-12-0110121835184310.18240/ijo.2017.12.08Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trialJin-Chao Liu0Li-Xia Luo1Bo Qu2Wei-Rong Chen3Yi-Zhi Liu4State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, ChinaState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China"AIM: To compare visual prognoses and postoperative adverse events of congenital cataract surgery performed at different times and using different surgical approaches. METHODS: In this prospective, randomized controlled trial, we recruited congenital cataract patients aged 3mo or younger before cataract surgery. Sixty-one eligible patients were randomly assigned to two groups according to surgical timing: a 3-month-old group and a 6-month-old group. Each eye underwent one of three randomly assigned surgical procedures, as follows: surgery A, lens aspiration (I/A); surgery B, lens aspiration with posterior continuous curvilinear capsulorhexis (I/A+PCCC); and surgery C, lens aspiration with posterior continuous curvilinear capsulorhexis and anterior vitrectomy (I/A+PCCC+A-Vit). The long-term best-corrected visual acuity (BCVA) and the incidence of complications in the different groups were compared and analyzed. RESULTS: A total of 57 participants (114 eyes) with a mean follow-up period of 48.7mo were included in the final analysis. The overall logMAR BCVA in the 6-month-old group was better than that in the 3-month-old group (0.81±0.28 vs 0.96±0.30; P=0.02). The overall logMAR BCVA scores in the surgery B group were lower than the scores in the A and C groups (A: 0.80±0.29, B: 1.02±0.28, and C: 0.84±0.28; P=0.007). A multivariate linear regression revealed no significant relationships between the incidence of complications and long-term BCVA. CONCLUSION: It might be safer and more beneficial for bilateral total congenital cataract patients to undergo surgery at 6mo of age than 3mo. Moreover, with rigorous follow-up and timely intervention, the postoperative complications in these patients are treatable and do not compromise visual outcomes." http://www.ijo.cn/en_publish/2017/12/20171208.pdf1843pediatric cataract surgerypostoperative complicationslong-term visual function |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jin-Chao Liu Li-Xia Luo Bo Qu Wei-Rong Chen Yi-Zhi Liu |
spellingShingle |
Jin-Chao Liu Li-Xia Luo Bo Qu Wei-Rong Chen Yi-Zhi Liu Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial International Journal of Ophthalmology 1843 pediatric cataract surgery postoperative complications long-term visual function |
author_facet |
Jin-Chao Liu Li-Xia Luo Bo Qu Wei-Rong Chen Yi-Zhi Liu |
author_sort |
Jin-Chao Liu |
title |
Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
title_short |
Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
title_full |
Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
title_fullStr |
Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
title_full_unstemmed |
Timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
title_sort |
timing and approaches in congenital cataract surgery: a four-year, two-layer randomized controlled trial |
publisher |
Press of International Journal of Ophthalmology (IJO PRESS) |
series |
International Journal of Ophthalmology |
issn |
2222-3959 2227-4898 |
publishDate |
2017-12-01 |
description |
"AIM: To compare visual prognoses and postoperative adverse events of congenital cataract surgery performed at different times and using different surgical approaches.
METHODS: In this prospective, randomized controlled trial, we recruited congenital cataract patients aged 3mo or younger before cataract surgery. Sixty-one eligible patients were randomly assigned to two groups according to surgical timing: a 3-month-old group and a 6-month-old group. Each eye underwent one of three randomly assigned surgical procedures, as follows: surgery A, lens aspiration (I/A); surgery B, lens aspiration with posterior continuous curvilinear capsulorhexis (I/A+PCCC); and surgery C, lens aspiration with posterior continuous curvilinear capsulorhexis and anterior vitrectomy (I/A+PCCC+A-Vit). The long-term best-corrected visual acuity (BCVA) and the incidence of complications in the different groups were compared and analyzed.
RESULTS: A total of 57 participants (114 eyes) with a mean follow-up period of 48.7mo were included in the final analysis. The overall logMAR BCVA in the 6-month-old group was better than that in the 3-month-old group (0.81±0.28 vs 0.96±0.30; P=0.02). The overall logMAR BCVA scores in the surgery B group were lower than the scores in the A and C groups (A: 0.80±0.29, B: 1.02±0.28, and C: 0.84±0.28; P=0.007). A multivariate linear regression revealed no significant relationships between the incidence of complications and long-term BCVA.
CONCLUSION: It might be safer and more beneficial for bilateral total congenital cataract patients to undergo surgery at 6mo of age than 3mo. Moreover, with rigorous follow-up and timely intervention, the postoperative complications in these patients are treatable and do not compromise visual outcomes."
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topic |
1843 pediatric cataract surgery postoperative complications long-term visual function |
url |
http://www.ijo.cn/en_publish/2017/12/20171208.pdf |
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