Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential
A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recu...
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Frontiers Media S.A.
2020-09-01
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Online Access: | https://www.frontiersin.org/article/10.3389/fvets.2020.576376/full |
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doaj-070ad5af4d8143519236de007fce1dd02020-11-25T03:14:14ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692020-09-01710.3389/fvets.2020.576376576376Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant PotentialCallie Blackford Winders0Cynthia M. Bell1Stephanie Goldschmidt2College of Veterinary Medicine, University of Minnesota, St. Paul, MN, United StatesSpecialty Oral Pathology for Animals, Geneseo, IL, United StatesCollege of Veterinary Medicine, University of Minnesota, St. Paul, MN, United StatesA 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity.https://www.frontiersin.org/article/10.3389/fvets.2020.576376/fullamyloid producing odontogenic tumorodontogenic tumorneoplasiadogspathology—head and neck neoplasms |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Callie Blackford Winders Cynthia M. Bell Stephanie Goldschmidt |
spellingShingle |
Callie Blackford Winders Cynthia M. Bell Stephanie Goldschmidt Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential Frontiers in Veterinary Science amyloid producing odontogenic tumor odontogenic tumor neoplasia dogs pathology—head and neck neoplasms |
author_facet |
Callie Blackford Winders Cynthia M. Bell Stephanie Goldschmidt |
author_sort |
Callie Blackford Winders |
title |
Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential |
title_short |
Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential |
title_full |
Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential |
title_fullStr |
Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential |
title_full_unstemmed |
Case Report: Amyloid-Producing Odontogenic Tumor With Pulmonary Metastasis in a Spinone Italiano—Proof of Malignant Potential |
title_sort |
case report: amyloid-producing odontogenic tumor with pulmonary metastasis in a spinone italiano—proof of malignant potential |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Veterinary Science |
issn |
2297-1769 |
publishDate |
2020-09-01 |
description |
A 1-year-old male Spinone Italiano dog was treated for an amyloid-producing odontogenic tumor on the right maxilla with a cytoreductive surgery followed by a definitive radiation protocol. Six years later, the dog presented for a new mass on the rostral mandible as well as a lung nodule without recurrence of the original maxillary tumor. Both the mandibular mass and the lung nodule were histologically confirmed to be amyloid-producing odontogenic tumor based on the appearance of sheets and cords of the odontogenic epithelium disrupted by amorphous extracellular amyloid. This case illustrates the metastatic potential for amyloid-producing odontogenic tumor in dogs and asynchronous occurrence of multiple APOTs in the oral cavity. |
topic |
amyloid producing odontogenic tumor odontogenic tumor neoplasia dogs pathology—head and neck neoplasms |
url |
https://www.frontiersin.org/article/10.3389/fvets.2020.576376/full |
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