Prion-derived copper-binding peptide fragments catalyze the generation of superoxide anion in the presence of aromatic monoamines
<p><b>Objectives: </b>Studies have proposed two opposing roles for copper-bound forms of prion protein (PrP) as an anti-oxidant supporting the neuronal functions and as a pro-oxidant leading to neurodegenerative process involving the generation of reactive oxygen species. The aim o...
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| Format: | Article |
| Language: | English |
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Ivyspring International Publisher
2007-01-01
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| Series: | International Journal of Biological Sciences |
| Online Access: | http://www.biolsci.org/v03p0057.htm |