Innovations in CAZyme gene diversity and its modification for biorefinery applications
For sustainable growth, concept of biorefineries as recourse to the “fossil derived” energy source is important. Here, the Carbohydrate Active enZymes (CAZymes) play decisive role in generation of biofuels and related sugar-based products utilizing lignocellulose as a carbon source. Given their indu...
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doaj-07185ca0f13b4143b6c6971b61eea09f2020-12-29T04:14:29ZengElsevierBiotechnology Reports2215-017X2020-12-0128e00525Innovations in CAZyme gene diversity and its modification for biorefinery applicationsDixita Chettri0Ashwani Kumar Verma1Anil Kumar Verma2Department of Microbiology, Sikkim University, IndiaDepartment of Microbiology, Sikkim University, IndiaCorresponding author at: Department of Microbiology, Sikkim University, Gangtok, 737102, Sikkim, India.; Department of Microbiology, Sikkim University, IndiaFor sustainable growth, concept of biorefineries as recourse to the “fossil derived” energy source is important. Here, the Carbohydrate Active enZymes (CAZymes) play decisive role in generation of biofuels and related sugar-based products utilizing lignocellulose as a carbon source. Given their industrial significance, extensive studies on the evolution of CAZymes have been carried out. Various bacterial and fungal organisms have been scrutinized for the development of CAZymes, where advance techniques for strain enhancement such as CRISPR and analysis of specific expression systems have been deployed. Specific Omic-based techniques along with protein engineering have been adopted to unearth novel CAZymes and improve applicability of existing enzymes. In-Silico computational research and functional annotation of new CAZymes to synergy experiments are being carried out to devise cocktails of enzymes for use in biorefineries. Thus, with the establishment of these technologies, increased diversity of CAZymes with broad span of functions and applications is seen.http://www.sciencedirect.com/science/article/pii/S2215017X20305403CAZymeOmicsCell factoriesConsolidated bioprocessingBiorefineries |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Dixita Chettri Ashwani Kumar Verma Anil Kumar Verma |
spellingShingle |
Dixita Chettri Ashwani Kumar Verma Anil Kumar Verma Innovations in CAZyme gene diversity and its modification for biorefinery applications Biotechnology Reports CAZyme Omics Cell factories Consolidated bioprocessing Biorefineries |
author_facet |
Dixita Chettri Ashwani Kumar Verma Anil Kumar Verma |
author_sort |
Dixita Chettri |
title |
Innovations in CAZyme gene diversity and its modification for biorefinery applications |
title_short |
Innovations in CAZyme gene diversity and its modification for biorefinery applications |
title_full |
Innovations in CAZyme gene diversity and its modification for biorefinery applications |
title_fullStr |
Innovations in CAZyme gene diversity and its modification for biorefinery applications |
title_full_unstemmed |
Innovations in CAZyme gene diversity and its modification for biorefinery applications |
title_sort |
innovations in cazyme gene diversity and its modification for biorefinery applications |
publisher |
Elsevier |
series |
Biotechnology Reports |
issn |
2215-017X |
publishDate |
2020-12-01 |
description |
For sustainable growth, concept of biorefineries as recourse to the “fossil derived” energy source is important. Here, the Carbohydrate Active enZymes (CAZymes) play decisive role in generation of biofuels and related sugar-based products utilizing lignocellulose as a carbon source. Given their industrial significance, extensive studies on the evolution of CAZymes have been carried out. Various bacterial and fungal organisms have been scrutinized for the development of CAZymes, where advance techniques for strain enhancement such as CRISPR and analysis of specific expression systems have been deployed. Specific Omic-based techniques along with protein engineering have been adopted to unearth novel CAZymes and improve applicability of existing enzymes. In-Silico computational research and functional annotation of new CAZymes to synergy experiments are being carried out to devise cocktails of enzymes for use in biorefineries. Thus, with the establishment of these technologies, increased diversity of CAZymes with broad span of functions and applications is seen. |
topic |
CAZyme Omics Cell factories Consolidated bioprocessing Biorefineries |
url |
http://www.sciencedirect.com/science/article/pii/S2215017X20305403 |
work_keys_str_mv |
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