A case of insulin-like growth factor 2-producing gastrointestinal stromal tumor with severe hypoglycemia

A case of insulin-like growth factor 2-producing gastrointestinal stromal tumor with severe hypoglycemia

Abstract Background Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome that secretes incompletely processed high molecular weight insulin growth factor 2 (big-IGF2), which results in stimulation of the insulin receptor and subsequently induces hypoglycemia. Gastrointestinal...

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Bibliographic Details
Main Authors: Haruka Yamasaki, Ayako Itawaki, Miwa Morita, Hitomi Miyake, Masahiro Yamamoto, Hiroki Sonoyama, Sayuri Tanaka, Masakazu Notsu, Mika Yamauchi, Yusuke Fujii, Noriyoshi Ishikawa, Izumi Fukuda, Shunji Ishihara, Keizo Kanasaki
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Endocrine Disorders
Subjects:
NICTH
GIST
Hypoglycemia
Big-IGF2
Online Access:http://link.springer.com/article/10.1186/s12902-020-0529-2

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