Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.

Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells.

TCR stimulation leads to an increase in cellular adhesion among other outcomes. The adhesion and degranulation promoting adapter protein (ADAP) is known to be rapidly phosphorylated after T cell stimulation and relays the TCR signal to adhesion molecules of the integrin family. While three tyrosine...

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Bibliographic Details
Main Authors: Marc Sylvester, Stefanie Kliche, Sabine Lange, Sabine Geithner, Clementine Klemm, Andreas Schlosser, Arndt Grossmann, Ulrich Stelzl, Burkhart Schraven, Eberhard Krause, Christian Freund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2908683?pdf=render

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http://europepmc.org/articles/PMC2908683?pdf=render

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