Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia
We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We obs...
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doaj-072ea6dcc27d49c9ae6bbf6fe8ac99982020-11-25T01:49:06ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592013-01-01191516010.3201/eid1901.120221Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular MalaysiaSohayati A. RahmanLatiffah HassanJonathan H. EpsteinZaini C. MamatAziz M. YatimSharifah S. HassanHume E. FieldTom HughesJustin WestrumM.S. NaimArshad S. SuriA. Aziz JamaluddinPeter DaszakWe conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We observed a consistently higher NiV risk (odds ratio 3.9) and seroprevalence (32.8%) for P. vampyrus than P. hypomelanus (11.1%) bats. A 3-year longitudinal study of P. hypomelanus bats indicated nonseasonal temporal variation in seroprevalence, evidence for viral circulation within the study period, and an overall NiV seroprevalence of 9.8%. The seroprevalence fluctuated over the study duration between 1% and 20% and generally decreased during 2004–2006. Adult bats, particularly pregnant, with dependent pup and lactating bats, had a higher prevalence of NiV antibodies than juveniles. Antibodies in juveniles 6 months–2 years of age suggested viral circulation within the study period.https://wwwnc.cdc.gov/eid/article/19/1/12-0221_articleNipah virusvirusesrisk factorsseroprevalenceinfectiondistribution |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sohayati A. Rahman Latiffah Hassan Jonathan H. Epstein Zaini C. Mamat Aziz M. Yatim Sharifah S. Hassan Hume E. Field Tom Hughes Justin Westrum M.S. Naim Arshad S. Suri A. Aziz Jamaluddin Peter Daszak |
spellingShingle |
Sohayati A. Rahman Latiffah Hassan Jonathan H. Epstein Zaini C. Mamat Aziz M. Yatim Sharifah S. Hassan Hume E. Field Tom Hughes Justin Westrum M.S. Naim Arshad S. Suri A. Aziz Jamaluddin Peter Daszak Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia Emerging Infectious Diseases Nipah virus viruses risk factors seroprevalence infection distribution |
author_facet |
Sohayati A. Rahman Latiffah Hassan Jonathan H. Epstein Zaini C. Mamat Aziz M. Yatim Sharifah S. Hassan Hume E. Field Tom Hughes Justin Westrum M.S. Naim Arshad S. Suri A. Aziz Jamaluddin Peter Daszak |
author_sort |
Sohayati A. Rahman |
title |
Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia |
title_short |
Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia |
title_full |
Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia |
title_fullStr |
Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia |
title_full_unstemmed |
Risk Factors for Nipah Virus Infection among Pteropid Bats, Peninsular Malaysia |
title_sort |
risk factors for nipah virus infection among pteropid bats, peninsular malaysia |
publisher |
Centers for Disease Control and Prevention |
series |
Emerging Infectious Diseases |
issn |
1080-6040 1080-6059 |
publishDate |
2013-01-01 |
description |
We conducted cross-sectional and longitudinal studies to determine the distribution of and risk factors for seropositivity to Nipah virus (NiV) among Pteropus vampyrus and P. hypomelanus bats in Peninsular Malaysia. Neutralizing antibodies against NiV were detected at most locations surveyed. We observed a consistently higher NiV risk (odds ratio 3.9) and seroprevalence (32.8%) for P. vampyrus than P. hypomelanus (11.1%) bats. A 3-year longitudinal study of P. hypomelanus bats indicated nonseasonal temporal variation in seroprevalence, evidence for viral circulation within the study period, and an overall NiV seroprevalence of 9.8%. The seroprevalence fluctuated over the study duration between 1% and 20% and generally decreased during 2004–2006. Adult bats, particularly pregnant, with dependent pup and lactating bats, had a higher prevalence of NiV antibodies than juveniles. Antibodies in juveniles 6 months–2 years of age suggested viral circulation within the study period. |
topic |
Nipah virus viruses risk factors seroprevalence infection distribution |
url |
https://wwwnc.cdc.gov/eid/article/19/1/12-0221_article |
work_keys_str_mv |
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