Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ1–42-Induced Rat Model of Alzheimer’s Disease

Icariin Attenuates Synaptic and Cognitive Deficits in an Aβ1–42-Induced Rat Model of Alzheimer’s Disease

Icariin (ICA), a prenylated flavanol glycoside present in abundant quantities in Epimedium sagittatum, has shown promise in the treatment and prevention of Alzheimer’s disease. Damage to synaptic plasticity induced by amyloid-beta-mediated neurotoxicity is considered a main pathological mechanism dr...

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Bibliographic Details
Main Authors:	Chenxia Sheng, Panpan Xu, Kexin Zhou, Dan Deng, Chunhu Zhang, Zhe Wang
Format:	Article
Language:	English
Published:	Hindawi Limited 2017-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2017/7464872

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