An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management...

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Main Authors: Bartolome R. Celli, Marc Decramer, Jadwiga A. Wedzicha, Kevin C. Wilson, Alvar A. Agustí, Gerard J. Criner, William MacNee, Barry J. Make, Stephen I. Rennard, Robert A. Stockley, Claus Vogelmeier, Antonio Anzueto, David H. Au, Peter J. Barnes, Pierre-Regis Burgel, Peter M. Calverley, Ciro Casanova, Enrico M. Clini, Christopher B. Cooper, Harvey O. Coxson, Daniel J. Dusser, Leonardo M. Fabbri, Bonnie Fahy, Gary T. Ferguson, Andrew Fisher, Monica J. Fletcher, Maurice Hayot, John R. Hurst, Paul W. Jones, Donald A. Mahler, François Maltais, David M. Mannino, Fernando J. Martinez, Marc Miravitlles, Paula M. Meek, Alberto Papi, Klaus F. Rabe, Nicolas Roche, Frank C. Sciurba, Sanjay Sethi, Nikos Siafakas, Don D. Sin, Joan B. Soriano, James K. Stoller, Donald P. Tashkin, Thierry Troosters, Geert M. Verleden, Johny Verschakelen, Jorgen Vestbo, John W. Walsh, George R. Washko, Robert A. Wise, Emiel F.M. Wouters, Richard L. ZuWallack
Format: Article
Language:English
Published: European Respiratory Society 2015-06-01
Series:European Respiratory Review
Online Access:http://err.ersjournals.com/content/24/136/159.full
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author Bartolome R. Celli
Marc Decramer
Jadwiga A. Wedzicha
Kevin C. Wilson
Alvar A. Agustí
Gerard J. Criner
William MacNee
Barry J. Make
Stephen I. Rennard
Robert A. Stockley
Claus Vogelmeier
Antonio Anzueto
David H. Au
Peter J. Barnes
Pierre-Regis Burgel
Peter M. Calverley
Ciro Casanova
Enrico M. Clini
Christopher B. Cooper
Harvey O. Coxson
Daniel J. Dusser
Leonardo M. Fabbri
Bonnie Fahy
Gary T. Ferguson
Andrew Fisher
Monica J. Fletcher
Maurice Hayot
John R. Hurst
Paul W. Jones
Donald A. Mahler
François Maltais
David M. Mannino
Fernando J. Martinez
Marc Miravitlles
Paula M. Meek
Alberto Papi
Klaus F. Rabe
Nicolas Roche
Frank C. Sciurba
Sanjay Sethi
Nikos Siafakas
Don D. Sin
Joan B. Soriano
James K. Stoller
Donald P. Tashkin
Thierry Troosters
Geert M. Verleden
Johny Verschakelen
Jorgen Vestbo
John W. Walsh
George R. Washko
Robert A. Wise
Emiel F.M. Wouters
Richard L. ZuWallack
spellingShingle Bartolome R. Celli
Marc Decramer
Jadwiga A. Wedzicha
Kevin C. Wilson
Alvar A. Agustí
Gerard J. Criner
William MacNee
Barry J. Make
Stephen I. Rennard
Robert A. Stockley
Claus Vogelmeier
Antonio Anzueto
David H. Au
Peter J. Barnes
Pierre-Regis Burgel
Peter M. Calverley
Ciro Casanova
Enrico M. Clini
Christopher B. Cooper
Harvey O. Coxson
Daniel J. Dusser
Leonardo M. Fabbri
Bonnie Fahy
Gary T. Ferguson
Andrew Fisher
Monica J. Fletcher
Maurice Hayot
John R. Hurst
Paul W. Jones
Donald A. Mahler
François Maltais
David M. Mannino
Fernando J. Martinez
Marc Miravitlles
Paula M. Meek
Alberto Papi
Klaus F. Rabe
Nicolas Roche
Frank C. Sciurba
Sanjay Sethi
Nikos Siafakas
Don D. Sin
Joan B. Soriano
James K. Stoller
Donald P. Tashkin
Thierry Troosters
Geert M. Verleden
Johny Verschakelen
Jorgen Vestbo
John W. Walsh
George R. Washko
Robert A. Wise
Emiel F.M. Wouters
Richard L. ZuWallack
An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
European Respiratory Review
author_facet Bartolome R. Celli
Marc Decramer
Jadwiga A. Wedzicha
Kevin C. Wilson
Alvar A. Agustí
Gerard J. Criner
William MacNee
Barry J. Make
Stephen I. Rennard
Robert A. Stockley
Claus Vogelmeier
Antonio Anzueto
David H. Au
Peter J. Barnes
Pierre-Regis Burgel
Peter M. Calverley
Ciro Casanova
Enrico M. Clini
Christopher B. Cooper
Harvey O. Coxson
Daniel J. Dusser
Leonardo M. Fabbri
Bonnie Fahy
Gary T. Ferguson
Andrew Fisher
Monica J. Fletcher
Maurice Hayot
John R. Hurst
Paul W. Jones
Donald A. Mahler
François Maltais
David M. Mannino
Fernando J. Martinez
Marc Miravitlles
Paula M. Meek
Alberto Papi
Klaus F. Rabe
Nicolas Roche
Frank C. Sciurba
Sanjay Sethi
Nikos Siafakas
Don D. Sin
Joan B. Soriano
James K. Stoller
Donald P. Tashkin
Thierry Troosters
Geert M. Verleden
Johny Verschakelen
Jorgen Vestbo
John W. Walsh
George R. Washko
Robert A. Wise
Emiel F.M. Wouters
Richard L. ZuWallack
author_sort Bartolome R. Celli
title An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
title_short An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
title_full An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
title_fullStr An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
title_full_unstemmed An official American Thoracic Society/European Respiratory Society statement: research questions in COPD
title_sort official american thoracic society/european respiratory society statement: research questions in copd
publisher European Respiratory Society
series European Respiratory Review
issn 0905-9180
1600-0617
publishDate 2015-06-01
description Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes.
url http://err.ersjournals.com/content/24/136/159.full
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spelling doaj-074508503fce4612b0f991002664fc9d2020-11-25T01:23:07ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172015-06-012413615917210.1183/16000617.0000031500315An official American Thoracic Society/European Respiratory Society statement: research questions in COPDBartolome R. Celli0Marc Decramer1Jadwiga A. Wedzicha2Kevin C. Wilson3Alvar A. Agustí4Gerard J. Criner5William MacNee6Barry J. Make7Stephen I. Rennard8Robert A. Stockley9Claus Vogelmeier10Antonio Anzueto11David H. Au12Peter J. Barnes13Pierre-Regis Burgel14Peter M. Calverley15Ciro Casanova16Enrico M. Clini17Christopher B. Cooper18Harvey O. Coxson19Daniel J. Dusser20Leonardo M. Fabbri21Bonnie Fahy22Gary T. Ferguson23Andrew Fisher24Monica J. Fletcher25Maurice Hayot26John R. Hurst27Paul W. Jones28Donald A. Mahler29François Maltais30David M. Mannino31Fernando J. Martinez32Marc Miravitlles33Paula M. Meek34Alberto Papi35Klaus F. Rabe36Nicolas Roche37Frank C. Sciurba38Sanjay Sethi39Nikos Siafakas40Don D. Sin41Joan B. Soriano42James K. Stoller43Donald P. Tashkin44Thierry Troosters45Geert M. Verleden46Johny Verschakelen47Jorgen Vestbo48John W. Walsh49George R. Washko50Robert A. Wise51Emiel F.M. Wouters52Richard L. ZuWallack53 Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Further details of this ATS/ERS Task Force for COPD Research can be found in the acknowledgements section Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient-centred outcomes.http://err.ersjournals.com/content/24/136/159.full