The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension

The Soluble Epoxide Hydrolase Inhibitor AR9281 Decreases Blood Pressure, Ameliorates Renal Injury and Improves Vascular Function in Hypertension

Soluble epoxide hydrolase inhibitors (sEHIs) are demonstrating promise as potential pharmaceutical agents for the treatment of cardiovascular disease, diabetes, inflammation, and kidney disease. The present study determined the ability of a first-inclass sEHI, AR9281, to decrease blood pressure, imp...

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Bibliographic Details
Main Authors: Sean Shaw, John D. Imig, Margaret A. Carpenter
Format: Article
Language:English
Published: MDPI AG 2009-12-01
Series:Pharmaceuticals
Subjects:
soluble epoxide hydrolase
eicosanoids
vascular
hypertension
kidney disease
Online Access:http://www.mdpi.com/1424-8247/2/3/217/

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