EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling.
In mouse cerebral corticogenesis, neurons are generated from radial glial cells (RGCs) or from their immediate progeny, intermediate neuronal precursors (INPs). The balance between self-renewal of these neuronal precursors and specification of cell fate is critical for proper cortical development, b...
Main Authors: | Qingfa Chen, Daiki Arai, Kazuki Kawakami, Takahiro Sawada, Xuefeng Jing, Masayasu Miyajima, Syu-Ichi Hirai, Kazushige Sakaguchi, Kenryo Furushima |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4433105?pdf=render |
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