In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia)
<p><span lang="IN">BDNF protein plays a role in the growth and survival of neurons. BDNF protein has some uniqueness</span><span lang="EN-US">,</span><span lang="IN"> and information on this protein is still limited reported</span&...
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doaj-07aca9f8ba1b44138ce4c4fb7de55aae2021-01-22T07:25:36ZindUniversitas Sultan Ageng TirtayasaEduChemia2502-47792502-47872020-01-0151202810.30870/educhemia.v5i1.67635274In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia)Ni Gusti Ayu Galuh Candra Kirana0I Made Budiarsa1I Nengah Kundera2Mohammad Jamhari3Program Studi Pendidikan Biologi P. MIPA, Universitas Tadulako, Jl.Soekarno-Hatta, PaluProgram Studi Pendidikan Biologi P. MIPA, Universitas Tadulako, Jl.Soekarno-Hatta, PaluProgram Studi Pendidikan Biologi P. MIPA, Universitas Tadulako, Jl.Soekarno-Hatta, PaluProgram Studi Pendidikan Biologi P. MIPA, Universitas Tadulako, Jl.Soekarno-Hatta, Palu<p><span lang="IN">BDNF protein plays a role in the growth and survival of neurons. BDNF protein has some uniqueness</span><span lang="EN-US">,</span><span lang="IN"> and information on this protein is still limited reported</span><span lang="EN-US">, </span><span lang="IN">especially in pigeons. The purpose of this study is to predict the three-dimensional structure of the </span><span lang="EN-US">pigeon of </span><span lang="IN"> BDNF protein, to provide information in understanding the characteristics, structure of the protein using a homology approach through in-silico analysis. The BDNF protein is predicted using the SWISS-MODEL server and visualizing the prediction results on the CHIMERA Software. Pigeon BDNF protein was taken from Uniprot with </span><span lang="EN-US">a </span><span lang="IN">B4Z8Q access code</span><span lang="IN">with a template of 1b8m.</span><span lang="EN-US">1. </span><span lang="IN">The analysis shows that BDNF protein </span><span lang="EN-US">has </span><span lang="IN"> an identity of 93,20% consisting of 226 amino acids with a target QMEAN value of -0.17 and hydrophobic amino acids namely Trp, His, Tyr, Ile, Leu, Gly, Lys, Cys, Ala, Phe, Met, and Val. Carboxyl residues</span><span lang="EN-US">,</span><span lang="IN"> namely Glu, Asp and Val, and amine residues</span><span lang="EN-US">,</span><span lang="IN"> namely Lys and Ser, with 82 hydrogen bonds.</span></p>https://jurnal.untirta.ac.id/index.php/EduChemia/article/view/6763bdnfthree dimensional of proteinhomology |
collection |
DOAJ |
language |
Indonesian |
format |
Article |
sources |
DOAJ |
author |
Ni Gusti Ayu Galuh Candra Kirana I Made Budiarsa I Nengah Kundera Mohammad Jamhari |
spellingShingle |
Ni Gusti Ayu Galuh Candra Kirana I Made Budiarsa I Nengah Kundera Mohammad Jamhari In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) EduChemia bdnf three dimensional of protein homology |
author_facet |
Ni Gusti Ayu Galuh Candra Kirana I Made Budiarsa I Nengah Kundera Mohammad Jamhari |
author_sort |
Ni Gusti Ayu Galuh Candra Kirana |
title |
In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) |
title_short |
In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) |
title_full |
In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) |
title_fullStr |
In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) |
title_full_unstemmed |
In-Silico Analysis of the BDNF (Brain Derived Neurotrophic Factor) Protein of Pigeon (Columba livia) |
title_sort |
in-silico analysis of the bdnf (brain derived neurotrophic factor) protein of pigeon (columba livia) |
publisher |
Universitas Sultan Ageng Tirtayasa |
series |
EduChemia |
issn |
2502-4779 2502-4787 |
publishDate |
2020-01-01 |
description |
<p><span lang="IN">BDNF protein plays a role in the growth and survival of neurons. BDNF protein has some uniqueness</span><span lang="EN-US">,</span><span lang="IN"> and information on this protein is still limited reported</span><span lang="EN-US">, </span><span lang="IN">especially in pigeons. The purpose of this study is to predict the three-dimensional structure of the </span><span lang="EN-US">pigeon of </span><span lang="IN"> BDNF protein, to provide information in understanding the characteristics, structure of the protein using a homology approach through in-silico analysis. The BDNF protein is predicted using the SWISS-MODEL server and visualizing the prediction results on the CHIMERA Software. Pigeon BDNF protein was taken from Uniprot with </span><span lang="EN-US">a </span><span lang="IN">B4Z8Q access code</span><span lang="IN">with a template of 1b8m.</span><span lang="EN-US">1. </span><span lang="IN">The analysis shows that BDNF protein </span><span lang="EN-US">has </span><span lang="IN"> an identity of 93,20% consisting of 226 amino acids with a target QMEAN value of -0.17 and hydrophobic amino acids namely Trp, His, Tyr, Ile, Leu, Gly, Lys, Cys, Ala, Phe, Met, and Val. Carboxyl residues</span><span lang="EN-US">,</span><span lang="IN"> namely Glu, Asp and Val, and amine residues</span><span lang="EN-US">,</span><span lang="IN"> namely Lys and Ser, with 82 hydrogen bonds.</span></p> |
topic |
bdnf three dimensional of protein homology |
url |
https://jurnal.untirta.ac.id/index.php/EduChemia/article/view/6763 |
work_keys_str_mv |
AT nigustiayugaluhcandrakirana insilicoanalysisofthebdnfbrainderivedneurotrophicfactorproteinofpigeoncolumbalivia AT imadebudiarsa insilicoanalysisofthebdnfbrainderivedneurotrophicfactorproteinofpigeoncolumbalivia AT inengahkundera insilicoanalysisofthebdnfbrainderivedneurotrophicfactorproteinofpigeoncolumbalivia AT mohammadjamhari insilicoanalysisofthebdnfbrainderivedneurotrophicfactorproteinofpigeoncolumbalivia |
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