High glucose alters retinal astrocytes phenotype through increased production of inflammatory cytokines and oxidative stress.

High glucose alters retinal astrocytes phenotype through increased production of inflammatory cytokines and oxidative stress.

Astrocytes are macroglial cells that have a crucial role in development of the retinal vasculature and maintenance of the blood-retina-barrier (BRB). Diabetes affects the physiology and function of retinal vascular cells including astrocytes (AC) leading to breakdown of BRB. However, the detailed ce...

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Bibliographic Details
Main Authors: Eui Seok Shin, Qiong Huang, Zafer Gurel, Christine M Sorenson, Nader Sheibani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4113377?pdf=render

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